research-article
Authors: Ping Chang, Huayu Li, Stuart F. Quan, Shuyang Lu, + 3, Shu-Fen Wung, Janet Roveda, and Ao Li (Less)
Volume 246, Issue C
Published: 25 June 2024 Publication History
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Abstract
Background and Objective
Vital sign monitoring in the Intensive Care Unit (ICU) is crucial for enabling prompt interventions for patients. This underscores the need for an accurate predictive system. Therefore, this study proposes a novel deep learning approach for forecasting Heart Rate (HR), Systolic Blood Pressure (SBP), and Diastolic Blood Pressure (DBP) in the ICU.
Methods
We extracted 24, 886 ICU stays from the MIMIC-III database which contains data from over 46 thousand patients, to train and test the model. The model proposed in this study, Transformer-based Diffusion Probabilistic Model for Sparse Time Series Forecasting (TDSTF), merges Transformer and diffusion models to forecast vital signs. The TDSTF model showed state-of-the-art performance in predicting vital signs in the ICU, outperforming other models' ability to predict distributions of vital signs and being more computationally efficient. The code is available at https://github.com/PingChang818/TDSTF.
Results
The results of the study showed that TDSTF achieved a Standardized Average Continuous Ranked Probability Score (SACRPS) of 0.4438 and a Mean Squared Error (MSE) of 0.4168, an improvement of 18.9% and 34.3% over the best baseline model, respectively. The inference speed of TDSTF is more than 17 times faster than the best baseline model.
Conclusion
TDSTF is an effective and efficient solution for forecasting vital signs in the ICU, and it shows a significant improvement compared to other models in the field.
Highlights
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The TDSTF model forecasts vital signs based on all events in the MIMIC-III dataset.
•
The proposed model captures temporal patterns in both slow and sudden changes.
•
The MSE of the model improves by 34.3% over the best baseline model.
•
The SACRPS of the model improves by 18.9% over the best baseline model.
•
The inference speed of the model is more than 17 times faster than the best baseline model.
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Information
Published In
Computer Methods and Programs in Biomedicine Volume 246, Issue C
Apr 2024
221 pages
ISSN:0169-2607
Issue’s Table of Contents
Elsevier B.V.
Publisher
Elsevier North-Holland, Inc.
United States
Publication History
Published: 25 June 2024
Author Tags
- Deep learning
- Time series forecasting
- Sparse data
- Vital signs
- ICU
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